Bryan Lee O'Malley is the creator of the super-ace comic
Scott Pilgrim, which has been getting a lot of (very well deserved) attention since it first came out in 2004. The 6-book series is not even finished yet, but it is already being adapted into a movie, and I bet will be in a lot of people's "best comics of 00s" list.
Prior to Scott Pilgrim, O'Malley illustrated the Oni Press mini-series Hopeless Savages: Ground Zero, and published his first graphic novel
Lost at Sea in 2003.
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www.scottpilgrim.com